CCSVI Clinic Physicians (www.ccsviclinic.ca) have applied for an International ethics
board study approval that will allow them to use the data on patients where their new
treatment protocol is being studied. Dr. Anand Alurkar, the Interventional Neurosurgeon
at Noble Hospital has done thousands of Intra and Extra cranial angio-procedures over
the past 10 years. His studies indicate that it’s critical to position and movement control
patients who have had venous angioplasty post-procedure, monitor them for days
afterward with various imaging techniques, for other symptoms, and re-treat if
necessary. CCSVI Clinic is already sponsoring patients for this protocol with a 10-day
stay in the hospital where patients will be imaged daily, post procedure. If there is
evidence of re-occlusion, they will be taken back to the OR and re-treated. Dr. Alurkar’s
past studies of non-MS patients with the same venous blockages have noted a cascade
of failure points distally in venous vessels post angioplasty, and he would expect that the
study with MS patients will produce the same results. His normal treatment regime
includes a protocol which includes a high concentration on post-procedure aftercare and
follow-up. To comply with the ethics board approval, once home, patients will be
examined and interviewed at regular intervals by CCSVI Clinic Physician Researchers for
several years after the treatment to study the changes.

More and more MS patients are reporting initial success (including vascular and some
neurological differences) as a result of the venous angioplasty (liberation therapy) but
then regression to previous symptoms sometimes within weeks post-procedure. It is
estimated that the failure rate of the “liberation therapy” may be 50% or higher, even
through the most experienced and best-known surgeons in Poland and Albany, NY.
Consequently, there is increasing concern amongst patients that the procedure
hypothesis needs to include a post-procedure protocol that is more effective than simply
releasing the patient from the hospital or clinic within hours or a day of the procedure. Dr.
Alurkar’s previous studies reveal there are many other considerations that indicate a
stabilization period, re-examination, and re-treatment if necessary. Where protocol is
followed, the current results have been consistently high enough to confirm Alurkar’s
hypothesis.

Furthermore, it’s the universal feeling of the physicians and researchers at Noble
Hospital, who are in a research partnership with CCSVI Clinic, (with offices and research
associates in Winnipeg, Toronto and Atlanta) that many corners are being cut by all big
clinics performing the procedure to take advantage of the over-whelming world-wide
demand for treatment in an opportunistic approach that focuses on hospital revenue. It is
also possible that these physicians, besides being drawn to the financial benefits of the
procedure, are unaware of the post-procedure hypothesis put forward by Dr. Alurkar for
his non-MS patient population studies.

Noble Hospital and CCSVI Clinic are expecting ethics board approval for their study
within 30 days and results will be released on an ongoing basis given the already high
interest in the findings. The goal with this study is to provide a prospective look at
patients undergoing the “liberation therapy” with the extended post-procedure protocol
and compare it to patients who receive minimal post-procedure surveillance.

Regular research updates will be published on the CCSVI Clinic website. Questions
may be directed toward the CCSVI Clinic administration at 1-888-419-6855. Persons
wishing to book a procedure should call the same number but should recognize that
they must participate in the study and will be followed for several years by the study
research team. Interested persons should ensure that applications are in as soon as
possible since there are limitations on the study population.